Arequipa is an important center of Peruvian arts and culture. Its downtown area, with buildings made of white volcanic rock (sillar) blending native and Spanish styles, is a UNESCO World Heritage site. Arequipa's Main Square (Plaza de Armas) is among Peru's most beautiful, with an impressive cathedral and colonial arcaded buildings full of restaurants and cafés.

A notable attraction near the square is the 400-year old Santa Catalina Monastery, which is like a city within the city. The Monastery will be the location of the LATIN 2012 banquet. Not too far from the bustling downtown area, there are quiet neighborhoods where you can take a pleasant stroll. One of these is Yanahuara, with a charming square and excellent view of the city, the mountains, and the surrounding countryside. Another is San Lazaro, with pedestrian streets and winding alleys. San Lazaro is the location of San Pablo Catholic University (UCSP) where LATIN 2012 will be held. The UCSP campus lies along the Chili River and has a clear view of the Misti volcano. All over the city there are excellent restaurants, where you can sample Arequipa's cuisine, which occupies a special place in Peru's world-renowned gastronomy.